Azithromycin is a macrolide antibiotic used to treat various bacterial infections. The Zaha brand of azithromycin is available in oral suspension form, making it suitable for children and adults who may have difficulty swallowing tablets. It works by inhibiting bacterial protein synthesis, effectively stopping the growth of bacteria.
Indications
Azithromycin oral suspension is indicated for:
- Respiratory Tract Infections: Such as pneumonia and bronchitis.
- Ear Infections: Including acute otitis media.
- Skin and Soft Tissue Infections: Such as cellulitis.
- Sexually Transmitted Infections: Including chlamydia and gonorrhea.
Dosage
- Adults:
- The typical dosage for most infections is 500 mg on the first day, followed by 250 mg once daily for the next 4 days (totaling 1.5 g).
- Alternatively, for some conditions, a single dose of 1 g may be prescribed.
- Children:
- Dosing is generally based on body weight. For example:
- For acute otitis media: 30 mg/kg as a single dose or 10 mg/kg once daily for 3 days.
- For community-acquired pneumonia: 10 mg/kg as a single dose on Day 1, followed by 5 mg/kg once daily on Days 2 through 5.
- For pharyngitis/tonsillitis in children aged 2 years and older: 12 mg/kg once daily for 5 days.
Administration
- How to Use:
- Shake the bottle well before each use to ensure proper mixing.
- Administer the suspension using a calibrated measuring device to ensure accurate dosing.
- Azithromycin can be taken with or without food, but taking it with food may help reduce gastrointestinal discomfort.
Common Side Effects
Possible side effects may include:
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
Serious side effects can include:
- Allergic reactions (e.g., rash, swelling, difficulty breathing)
- Liver problems (e.g., jaundice)
- Heart rhythm changes (QT prolongation)
Warnings and Precautions
- Contraindications: Not suitable for individuals with a known allergy to azithromycin or other macrolide antibiotics.
- Liver Function: Use with caution in patients with liver impairment; monitoring may be necessary during treatment.
- Heart Rhythm Issues: Azithromycin may cause QT prolongation; use with caution in patients with existing heart conditions or those taking medications that affect heart rhythm.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if you are pregnant or breastfeeding.
Drug Interactions
Inform your healthcare provider about all medications you are taking, especially:
- Antacids containing aluminum or magnesium (may interfere with absorption)
- Other medications that prolong QT interval
Storage
Store Azithromycin oral suspension at room temperature (15° to 30°C), away from moisture and direct sunlight. After reconstitution, it should be refrigerated and used within a specified period (usually within 7 days). Keep out of reach of children.
