Ampiclox is a combination antibiotic that contains ampicillin and cloxacillin. This formulation is effective against a wide range of bacterial infections, particularly those caused by both Gram-positive and Gram-negative bacteria. It is commonly used to treat various infections due to its broad-spectrum activity.
Composition:
- Each capsule contains:
- 250 mg of Ampicillin (as Ampicillin Trihydrate)
- 250 mg of Cloxacillin (as Cloxacillin Sodium)
Indications
Ampiclox is indicated for the treatment of:
- Respiratory Tract Infections: Such as pneumonia and bronchitis.
- Ear Infections: Including otitis media.
- Skin and Soft Tissue Infections: Effective against various skin infections.
- Urinary Tract Infections: Such as cystitis and pyelonephritis.
- Bone and Joint Infections: Including osteomyelitis.
Dosage
The typical dosage for adults is:
- For Mild to Moderate Infections: 500 mg every 6 hours or as directed by a healthcare provider.
- For More Severe Infections: Higher doses may be prescribed based on the severity and type of infection.
Administration
- How to Take: Ampiclox capsules should be taken orally with a full glass of water. It can be taken with or without food, but taking it with food may help reduce gastrointestinal upset.
- Missed Dose: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Common Side Effects
Possible side effects may include:
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Rash or itching
Serious side effects are rare but can include:
- Severe allergic reactions (e.g., hives, difficulty breathing)
- Clostridium difficile-associated diarrhea
- Liver dysfunction (symptoms may include jaundice or dark urine)
Warnings and Precautions
Allergic Reactions
Patients should be aware of potential allergic reactions such as:
- Skin rash or hives
- Swelling of the face, lips, or throat (angioedema)
- Difficulty breathing
At-Risk Populations:
- Pregnant Women: Should consult a healthcare provider before use.
- Patients with Liver Disease or Renal Impairment: Caution is advised, and dosage adjustments may be necessary.
Drug Interactions
Ampiclox may interact with other medications, particularly:
- Anticoagulants: May enhance the effects of blood thinners like warfarin.
- Other Antibiotics: Use caution when combining with other antibiotics.
