Cefuroxime (Furocef) is a second-generation cephalosporin antibiotic that is effective against a variety of bacterial infections. Each tablet contains 500 mg of cefuroxime and is commonly used to treat infections in different parts of the body.
Key Uses
Cefuroxime is indicated for the treatment of:
- Respiratory Tract Infections: Including pneumonia, bronchitis, and sinusitis.
- Ear Infections: Such as otitis media.
- Skin and Soft Tissue Infections: Effective for conditions like cellulitis and abscesses.
- Urinary Tract Infections (UTIs): Treats infections of the urinary system.
- Gonorrhea: Used for treating uncomplicated gonococcal infections.
- Bone and Joint Infections: Such as osteomyelitis.
Mechanism of Action
Cefuroxime works by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins inside the bacterial cell wall, disrupting the formation of the cell wall, leading to cell lysis and death.
Dosage and Administration
- Adults: The usual dosage for adults is typically 500 mg every 12 hours, but this may vary based on the type and severity of the infection.
- Children: Dosage for pediatric patients should be determined by a healthcare provider based on weight and age.
Cefuroxime tablets should be taken orally with a glass of water, preferably after food to enhance absorption and minimize gastrointestinal discomfort.
Side Effects
Common side effects may include:
- Nausea
- Diarrhea
- Abdominal pain
- Dizziness
- Headache
Serious side effects can include allergic reactions (such as rash, itching, or difficulty breathing), Clostridium difficile-associated diarrhea, and liver enzyme elevation.
Warnings and Precautions
- Contraindications: Not suitable for individuals with known hypersensitivity to cefuroxime or other cephalosporins. Caution is advised for those with a history of penicillin allergy.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
- Renal Impairment: Dosage adjustments may be necessary for patients with kidney issues.
Storage
Store Cefuroxime (Furocef) tablets at room temperature (below 25°C), away from moisture and direct sunlight. Keep out of reach of children.
