Clarinase is a combination medication primarily used to relieve symptoms associated with allergic rhinitis and the common cold. Each tablet typically contains 5 mg of loratadine (an antihistamine) and 120 mg of pseudoephedrine (a decongestant). The package usually contains 14 tablets.
Key Uses
Clarinase is indicated for:
- Allergic Rhinitis: Relief from symptoms such as sneezing, runny nose, and itchy/watery eyes.
- Nasal Congestion: Effective in reducing nasal congestion due to colds or allergies.
- Sinus Pressure: Helps alleviate pressure and discomfort associated with sinus congestion.
Mechanism of Action
- Loratadine: Works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
- Pseudoephedrine: Acts as a decongestant by constricting blood vessels in the nasal passages, which reduces swelling and congestion.
Dosage and Administration
- Adults and Children (12 years and older): The usual dosage is 1 tablet every 12 hours, not exceeding 2 tablets in 24 hours.
- Children under 12 years: Not recommended for use in this age group without consulting a healthcare provider.
The tablets can be taken with or without food. It is important to follow the prescribed dosage and not exceed the recommended amount.
Side Effects
Common side effects may include:
- Dry mouth
- Dizziness
- Fatigue
- Insomnia
- Increased heart rate
- Nervousness
- Nausea
Serious side effects are rare but can include:
- Severe allergic reactions (anaphylaxis)
- High blood pressure or arrhythmias
Warnings and Precautions
- Contraindications: Not suitable for individuals with known hypersensitivity to loratadine, pseudoephedrine, or any other components of Clarinase.
- Caution in Specific Populations: Use cautiously in patients with hypertension, heart disease, diabetes, thyroid disorders, or those taking monoamine oxidase inhibitors (MAOIs).
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
Storage
Store Clarinase tablets at room temperature (below 25°C), away from moisture and direct sunlight. Keep out of reach of children.
