Cetamol is an oral suspension that typically contains paracetamol (acetaminophen), which is widely used as an analgesic (pain reliever) and antipyretic (fever reducer). The 60ml syrup formulation is commonly used to relieve mild to moderate pain and reduce fever, particularly in children.
Key Uses
Cetamol syrup is indicated for:
- Fever Reduction: Effective in lowering body temperature during fever.
- Pain Relief: Used for mild to moderate pain, including headaches, toothaches, muscle aches, and pain associated with colds or flu.
Mechanism of Action
Paracetamol works by inhibiting the synthesis of prostaglandins in the brain, which are chemicals that promote inflammation, pain, and fever. By reducing the production of these substances, paracetamol effectively alleviates pain and lowers fever.
Dosage and Administration
- Adults: The usual dosage is 500 mg to 1000 mg every 4 to 6 hours, not exceeding 4000 mg per day.
- Children: The dosage for children is typically based on weight:
- Infants (under 2 years): Consult a healthcare provider for appropriate dosing.
- Children aged 2-12 years: Generally, 10-15 mg/kg every 4 to 6 hours, not exceeding the maximum daily dose.
For example:
- 3 to 5 months: 2.5 ml up to 4 times a day.
- 6 to 23 months: 5 ml up to 4 times a day.
- 2 to 3 years: 7.5 ml up to 4 times a day.
- 4 to 5 years: 10 ml up to 4 times a day.
The syrup should be shaken well before use and can be taken with or without food. It is important to measure the dose accurately using a dosing syringe or cup.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Allergic reactions (rare)
- Skin rash (rare)
Serious side effects are uncommon when used at recommended doses but can occur in cases of overdose, leading to liver damage.
Warnings and Precautions
- Contraindications: Not suitable for individuals with known hypersensitivity to paracetamol or any other components of the syrup.
- Liver Disease: Caution is advised in patients with liver impairment or chronic alcoholism, as they may be at increased risk of liver toxicity.
- Pregnancy and Breastfeeding: Generally considered safe during pregnancy and breastfeeding when used at recommended doses. However, consult a healthcare provider before use.
Storage
Store Cetamol syrup at room temperature (below 25°C), away from moisture and direct sunlight. After opening, use within a specified period (usually indicated on the packaging).