Carvidolol is a medication that contains carvedilol, a non-selective beta-blocker and alpha-1 blocker, primarily used for the management of hypertension (high blood pressure) and heart failure. The formulation typically comes in a pack of 30 tablets, each containing 12.5 mg of carvedilol.
Key Uses
- Hypertension: Effective in lowering blood pressure, which helps reduce the risk of heart attack and stroke.
- Heart Failure: Improves heart function and reduces symptoms in patients with heart failure.
- Angina Pectoris: Helps relieve chest pain by decreasing the workload on the heart.
Mechanism of Action
Carvedilol works by:
- Blocking Beta Receptors: Reduces heart rate and myocardial contractility, leading to decreased cardiac output.
- Blocking Alpha-1 Receptors: Causes vasodilation (widening of blood vessels), which further lowers blood pressure.
Dosage and Administration
- Initial Dosage: The usual starting dose for adults is 12.5 mg once daily, which may be adjusted based on the patient's response.
- Administration: It is recommended to take Carvidolol with food to enhance absorption and minimize potential side effects such as dizziness.
Side Effects
Common side effects may include:
- Dizziness or lightheadedness
- Fatigue
- Nausea or vomiting
- Diarrhea
- Low blood pressure (hypotension)
- Bradycardia (slow heart rate)
Serious side effects can include severe allergic reactions, liver dysfunction, or worsening heart failure symptoms. Patients should be monitored for these potential issues.
Warnings and Precautions
- Contraindications: Not suitable for individuals with known hypersensitivity to carvedilol or those with severe liver impairment.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding, as carvedilol may pose risks during these periods.
- Abrupt Discontinuation: Do not stop taking Carvidolol suddenly; this can lead to rebound hypertension or exacerbation of angina.
Storage
Store Carvidolol tablets at room temperature (below 25°C), away from moisture and direct sunlight. Keep out of reach of children.
