Doxy 100mg Capsules contain Doxycycline, a broad-spectrum antibiotic belonging to the tetracycline group. It is effective against a wide range of Gram-positive and Gram-negative bacteria and is commonly used to treat various infections.
Key Features
- Active Ingredient: Each capsule contains 100 mg of Doxycycline.
- Formulation: Hard gelatin capsules, typically available in packs of 10x10 capsules (100 capsules total).
Indications
Doxycycline is indicated for the treatment of various infections, including:
- Respiratory Tract Infections: Such as pneumonia, bronchitis, and sinusitis.
- Gastrointestinal Tract Infections: Including cholera, traveler's diarrhea, and shigella dysentery.
- Chlamydial Infections: Such as non-gonococcal urethritis and pelvic inflammatory disease.
- Skin Infections: Including acne and impetigo.
- Other Infections: Such as brucellosis, tularemia, and certain sexually transmitted diseases.
Mechanism of Action
Doxycycline works by inhibiting protein synthesis in bacteria, effectively stopping their growth and multiplication. It is bacteriostatic, meaning it prevents bacteria from reproducing rather than killing them outright.
Dosage and Administration
- Usual Dosage:
- For most infections, the typical initial dose is 200 mg on the first day, followed by 100 mg daily for 7-10 days.
- For severe infections, a higher dose may be required.
- For acne treatment, a common regimen is 100 mg daily.
- Administration Instructions: Capsules should be swallowed whole with plenty of fluids during meals while sitting or standing to minimize the risk of esophageal irritation.
Side Effects
Common side effects may include:
- Nausea and vomiting
- Diarrhea
- Skin rashes
- Photosensitivity (increased sensitivity to sunlight)
Serious side effects can include:
- Severe allergic reactions (e.g., rash, swelling)
- Esophageal irritation or ulceration if not taken with sufficient water
- Changes in blood counts (e.g., hemolytic anemia)
If any severe reactions occur, discontinue use immediately and seek medical attention.
Contraindications
Doxycycline should not be used in individuals who:
- Have a known hypersensitivity to doxycycline or other tetracyclines.
- Are pregnant or breastfeeding unless prescribed by a healthcare provider.
- Are children under 8 years of age due to the risk of teeth discoloration.
Interactions
Doxycycline may interact with:
- Antacids containing aluminum, calcium, or magnesium, which can impair absorption.
- Iron supplements and bismuth salicylate can also reduce absorption.
- Certain medications like barbiturates or phenytoin may decrease doxycycline's effectiveness.
