Ketoconazole is an antifungal medication commonly used to treat various fungal infections. The 10x10 tablets packaging indicates that the product contains 10 tablets, typically used for systemic treatment of infections.
Key Features
- Active Ingredient: Each tablet contains 200 mg or 400 mg of ketoconazole, depending on the specific formulation.
- Formulation: Available in tablet form, making it easy to administer.
- Mechanism of Action: Ketoconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, which disrupts fungal growth.
Indications
Ketoconazole is indicated for:
- Fungal Infections: Treatment of systemic fungal infections such as:
- Candidiasis (thrush and other yeast infections)
- Blastomycosis
- Histoplasmosis
- Coccidioidomycosis
- Dermatophyte Infections: Effective against skin infections like ringworm and athlete's foot.
Dosage and Administration
- Recommended Dosage: The typical adult dosage ranges from 200 mg to 400 mg daily, depending on the severity of the infection and the prescribing physician's recommendations.
- Administration Instructions: Tablets should be taken with food to enhance absorption and reduce gastrointestinal side effects.
Side Effects
Common side effects may include:
- Nausea and vomiting
- Abdominal pain or discomfort
- Diarrhea
- Headache
- Dizziness
Serious side effects can include:
- Liver toxicity (monitoring liver function is recommended)
- Allergic reactions (e.g., rash, difficulty breathing)
- Changes in heart rhythm (QT prolongation)
Precautions
- Liver Function Monitoring: Due to potential hepatotoxicity, liver function tests may be necessary during treatment.
- Drug Interactions: Ketoconazole can interact with various medications, particularly those metabolized by the liver. It is important to inform healthcare providers about all medications being taken.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
