Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. It is effective for various conditions, including arthritis, muscle pain, menstrual cramps, and gout.
Key Uses
Naproxen is indicated for:
- Arthritis: Effective for rheumatoid arthritis and osteoarthritis.
- Muscle Pain: Provides relief from strains, sprains, and other muscle-related discomfort.
- Menstrual Cramps: Alleviates pain associated with dysmenorrhea.
- Gout Attacks: Helps reduce pain and inflammation during acute gout episodes.
- Other Pain Conditions: Useful for headaches, dental pain, and back pain.
Mechanism of Action
Naproxen works by inhibiting the production of prostaglandins, which are chemicals in the body that promote inflammation, pain, and fever. By blocking these substances, naproxen effectively reduces inflammation and alleviates pain.
Dosage and Administration
- Recommended Dosage: The typical dosage for adults is often 250 mg to 500 mg, taken every 12 hours as needed. However, the specific dosage may vary based on the condition being treated and individual patient factors.
- Administration Instructions: It is advisable to take naproxen with food or milk to minimize gastrointestinal irritation. The tablets should be swallowed whole with a full glass of water.
Side Effects
Common side effects may include:
- Indigestion or heartburn
- Stomach pain
- Nausea
- Dizziness or drowsiness
- Headache
Serious side effects can include:
- Increased risk of heart attack or stroke, especially with long-term use or in individuals with existing heart conditions.
- Gastrointestinal bleeding or ulcers.
- Allergic reactions such as rash, swelling, or difficulty breathing.
Precautions
- Contraindications: Avoid use in individuals with a history of allergic reactions to NSAIDs or those with certain medical conditions such as severe heart disease or active gastrointestinal bleeding.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
- Drug Interactions: Inform your healthcare provider about all medications being taken to avoid potential interactions.