Meloxicam, marketed under the brand name M-CAM, is a nonsteroidal anti-inflammatory drug (NSAID) used primarily for the relief of pain and inflammation associated with various types of arthritis. Each tablet contains 15 mg of meloxicam, and the packaging typically consists of 1x200 tablets.
Key Uses
Meloxicam is indicated for:
- Osteoarthritis: Helps alleviate pain and stiffness caused by the degeneration of joint cartilage.
- Rheumatoid Arthritis: Reduces inflammation and discomfort associated with this autoimmune condition.
- Juvenile Rheumatoid Arthritis: Used in children aged 2 years and older to manage symptoms.
Mechanism of Action
Meloxicam works by inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the production of prostaglandins. Prostaglandins are compounds that promote inflammation, pain, and fever. By reducing their production, meloxicam effectively decreases pain and inflammation.
Dosage and Administration
- Recommended Dosage: The typical starting dose for adults is 15 mg once daily. Depending on the patient's response, it may be reduced to 7.5 mg once daily.
- Administration Instructions:
- Take meloxicam with food or milk to minimize gastrointestinal discomfort.
- Swallow the tablet whole with a full glass of water; do not crush or chew.
Side Effects
Common side effects may include:
- Abdominal pain
- Diarrhea
- Nausea
- Dizziness
- Headache
Serious side effects can include:
- Increased risk of cardiovascular events (e.g., heart attack, stroke)
- Gastrointestinal bleeding or ulcers
- Liver or kidney problems
- Severe allergic reactions (e.g., hives, difficulty breathing)
Precautions
- Contraindications: Avoid use in individuals with known hypersensitivity to meloxicam or other NSAIDs. It should not be used just before or after heart bypass surgery.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
- Drug Interactions: Inform your healthcare provider about all medications you are taking, as meloxicam can interact with other drugs, including anticoagulants and certain antihypertensives.
