Ofloxacin is a broad-spectrum antibiotic belonging to the fluoroquinolone class, primarily used to treat various bacterial infections. The 10x10 tablet packaging indicates that the medication is typically available in a box containing 10 tablets, with each tablet generally containing 200 mg or 400 mg of Ofloxacin.
Key Uses
Ofloxacin is indicated for the treatment of:
- Urinary Tract Infections (UTIs): Effective against infections affecting the bladder and kidneys.
- Respiratory Tract Infections: Used for bacterial pneumonia and bronchitis.
- Skin and Soft Tissue Infections: Treats infections of the skin and underlying tissues.
- Gastrointestinal Infections: Effective against certain types of bacterial diarrhea.
- Sexually Transmitted Infections: Particularly effective against gonorrhea and chlamydia.
Mechanism of Action
Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and repair. This action disrupts the replication process, leading to bacterial cell death.
Dosage and Administration
- Typical Dosage:
- Adults: Usually prescribed 200 mg to 400 mg every 12 hours, depending on the type and severity of the infection. For gonorrhea, a single dose of 400 mg may be sufficient.
- Duration of treatment can range from 3 days to 6 weeks, based on the specific infection being treated.
- Administration Instructions:
- Take the tablets with a full glass of water.
- It can be taken with or without food, but dairy products should be avoided close to the time of taking the medication as they can interfere with absorption.
Side Effects
Common side effects may include:
- Nausea
- Diarrhea
- Headache
- Dizziness
- Insomnia
- Rash or itching
Serious side effects can include:
- Tendon rupture or tendinitis
- Peripheral neuropathy (nerve damage)
- Mood changes (anxiety, confusion)
- Severe allergic reactions (hives, difficulty breathing)
Patients should seek immediate medical attention if they experience symptoms such as sudden joint pain, severe dizziness, or signs of an allergic reaction.
Precautions
- Contraindications: Should not be used in individuals with a known allergy to fluoroquinolones. Caution is advised in patients with a history of tendon disorders or myasthenia gravis.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding.
