Salbactamox is a combination antibiotic injection that includes sulbactam and ampicillin. This formulation is designed to treat various bacterial infections by enhancing the efficacy of ampicillin against beta-lactamase-producing bacteria.
Key Components
- Sulbactam: A beta-lactamase inhibitor that protects ampicillin from degradation by bacterial enzymes, thereby extending its antibacterial spectrum.
- Ampicillin: A penicillin-type antibiotic that works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death.
Mechanism of Action
- Sulbactam binds irreversibly to beta-lactamase enzymes produced by certain bacteria, preventing them from breaking down ampicillin.
- This combination allows ampicillin to effectively target a broader range of bacteria, including those that are resistant due to beta-lactamase production.
Indications
Salbactamox is indicated for the treatment of:
- Skin and Soft Tissue Infections: Effective against various pathogens causing skin infections.
- Respiratory Tract Infections: Useful in treating pneumonia and other respiratory infections.
- Intra-abdominal Infections: Effective for conditions such as peritonitis or abscesses.
- Gynecological Infections: Treats infections of the female reproductive system.
Dosage Instructions
- The dosage of Salbactamox 1.5mg injection will depend on the specific condition being treated, the severity of the infection, and patient factors such as age and weight.
- It is typically administered intravenously or intramuscularly, with healthcare providers determining the appropriate frequency and duration of treatment.
Side Effects
Common side effects may include:
- Nausea or vomiting
- Diarrhea
- Allergic reactions (rash, itching)
- Changes in liver function tests
Serious side effects can include:
- Severe allergic reactions (anaphylaxis)
- Clostridium difficile-associated diarrhea
Precautions
- Contraindications: Not recommended for individuals with a known allergy to penicillins or cephalosporins.
- Use with caution in patients with renal impairment or a history of gastrointestinal diseases.
- Monitor for signs of allergic reactions during treatment.
