SANIX is a brand name for Cefixime, a third-generation cephalosporin antibiotic used to treat a variety of bacterial infections. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a versatile option in clinical settings.
Key Features
- Active Ingredient: Each tablet contains 400 mg of Cefixime.
- Formulation: Typically available in tablet form for oral administration.
- Mechanism of Action: Cefixime works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is stable against certain beta-lactamase enzymes, allowing it to be effective against some resistant strains.
Indications
Cefixime is indicated for the treatment of:
- Uncomplicated Urinary Tract Infections (UTIs): Caused by susceptible strains of Escherichia coli and Proteus mirabilis.
- Otitis Media: Middle ear infections caused by Haemophilus influenzae and Moraxella catarrhalis.
- Pharyngitis and Tonsillitis: Infections caused by Streptococcus pyogenes.
- Acute Exacerbations of Chronic Bronchitis: Particularly in patients with COPD.
- Gonorrhea: Uncomplicated infections caused by Neisseria gonorrhoeae.
Dosage Instructions
- Adults: The usual dose is 400 mg once daily or can be divided into two doses of 200 mg every 12 hours, depending on the severity of the infection.
- Children: Dosage may vary based on age and weight; typically, it is calculated based on body weight.
Side Effects
Common side effects may include:
- Diarrhea
- Nausea and vomiting
- Abdominal pain or discomfort
- Headache
- Rash or allergic reactions
Serious side effects can include:
- Severe allergic reactions (anaphylaxis)
- Clostridium difficile-associated diarrhea (CDAD)
- Liver dysfunction (jaundice)
- Kidney problems
Patients should seek immediate medical attention if they experience severe side effects or signs of an allergic reaction, such as difficulty breathing or swelling of the face and throat.
Precautions
- Contraindications: Not recommended for individuals with known hypersensitivity to cefixime, other cephalosporins, or penicillin antibiotics.
- Use with caution in patients with renal impairment, gastrointestinal disease (especially colitis), or those on anticoagulant therapy.
- Patients should inform their healthcare provider about any other medications they are taking to avoid potential interactions.
