Quinine Syrup is a medication primarily used for the treatment of malaria and sometimes for managing nocturnal leg cramps. It contains quinine sulfate as the active ingredient, which is effective against certain strains of the malaria parasite.
Key Features
- Active Ingredient: Each 5 mL of syrup typically contains 200 mg of Quinine Sulfate, but this can vary based on the formulation.
- Pack Size: Available in a 100 mL bottle.
Indications
Quinine Syrup is indicated for:
- Treatment of Malaria: Effective against uncomplicated malaria caused by Plasmodium falciparum and other malaria parasites.
- Nocturnal Leg Cramps: Sometimes prescribed off-label for the relief of muscle cramps at night, although this use is controversial due to potential side effects.
Dosage Instructions
- Adults: The usual dosage for malaria is typically 600 mg (30 mL) taken orally every 8 hours for 7 days. For nocturnal leg cramps, a common dosage is 200 mg (10 mL) at bedtime.
- Children: Dosing is usually based on weight, often around 10 mg/kg every 8 hours for malaria treatment.
Administration
- Shake the bottle well before use to ensure proper mixing of the medication.
- Measure the dose accurately using a proper measuring device; do not use household spoons.
- Take with food to minimize gastrointestinal discomfort.
Side Effects
Common side effects may include:
- Nausea and vomiting
- Diarrhea
- Headache
- Tinnitus (ringing in the ears)
- Blurred vision
Serious side effects can include:
- Severe allergic reactions (e.g., rash, difficulty breathing)
- Thrombocytopenia (low platelet count)
- Hemolytic uremic syndrome (a serious condition affecting the kidneys)
- Cardiac arrhythmias
Precautions
- Contraindications: Not recommended for individuals with known hypersensitivity to quinine or those with certain medical conditions such as myasthenia gravis, optic neuritis, or a history of blood disorders related to quinine.
- Use caution in patients with renal impairment; dosage adjustments may be necessary.
- Pregnant or breastfeeding women should consult a healthcare provider before use.
