P-Alaxin Syrup is an antimalarial medication used for the treatment of uncomplicated malaria, particularly caused by Plasmodium falciparum. This syrup formulation is designed for easy administration, especially in children or individuals who have difficulty swallowing tablets.
Key Ingredients
- Dihydroartemisinin: A fast-acting antimalarial agent derived from artemisinin, effective in rapidly reducing the parasite load in the bloodstream.
- Piperaquine Phosphate: A longer-acting antimalarial that helps eliminate residual parasites and prevent reinfection.
Mechanism of Action
- Dihydroartemisinin works by disrupting the malaria parasite's metabolism, leading to its death.
- Piperaquine enhances the efficacy of dihydroartemisinin by providing prolonged action, ensuring that any remaining parasites are cleared from the body.
Dosage and Administration
- Recommended Dosage: The dosage is typically based on the patient's weight. For example:
- A child weighing 5 kg may take 12.5 ml once daily.
- A child weighing 10 kg may take 25 ml once daily.
- Administration Instructions: Shake well before use. Measure the dose accurately using a proper measuring device. It is usually taken once daily for three consecutive days.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Dizziness
Serious side effects are rare but can include:
- Allergic reactions (e.g., rash, swelling)
- Heart rhythm abnormalities (QT prolongation)
Precautions
- Contraindications: Not recommended for individuals with known allergies to dihydroartemisinin or piperaquine. Use caution in patients with a history of heart problems or liver disease.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.
- Drug Interactions: Inform your healthcare provider about all medications you are taking, as P-Alaxin may interact with other drugs.
