P-Alaxin is an antimalarial medication that combines Dihydroartemisinin and Piperaquine Phosphate, primarily used for the treatment of uncomplicated malaria caused by Plasmodium falciparum. The formulation typically comes in packs containing 2 tablets, making it suitable for short treatment courses.
Key Ingredients
- Dihydroartemisinin: A potent antimalarial agent derived from artemisinin, known for its rapid action against malaria parasites.
- Piperaquine Phosphate: A longer-acting antimalarial that complements the action of dihydroartemisinin, helping to eliminate residual parasites and prevent reinfection.
Mechanism of Action
- Dihydroartemisinin works quickly to reduce the parasite load in the bloodstream, while Piperaquine provides prolonged action to ensure that any remaining parasites are eliminated, thus reducing the risk of recurrence.
Dosage and Administration
- Recommended Dosage: The standard regimen involves taking 1 tablet once daily for 3 consecutive days. The exact dosage may vary based on the patient's weight and the severity of the infection.
- Administration Instructions: Take the tablets with water, preferably with food to minimize gastrointestinal discomfort.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Dizziness
- Fatigue
- Abdominal pain
Serious side effects are rare but can include:
- Allergic reactions (e.g., rash, swelling)
- Heart rhythm abnormalities (QT prolongation)
Precautions
- Contraindications: Not recommended for individuals with known allergies to dihydroartemisinin or piperaquine. Caution is advised for those with a history of heart problems or liver disease.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.
- Drug Interactions: Inform your healthcare provider about all medications you are taking, as P-Alaxin may interact with other drugs.
