Telmisartan 80-H, commonly marketed under the brand name Arbitel 80-H, is an antihypertensive medication that combines telmisartan and hydrochlorothiazide. This combination is used to effectively manage high blood pressure (hypertension), particularly in patients who do not achieve adequate control with a single medication.
Key Features
- Active Ingredients:
- Telmisartan: An angiotensin II receptor blocker (ARB) that relaxes blood vessels, lowering blood pressure.
- Hydrochlorothiazide: A thiazide diuretic that helps reduce fluid retention by increasing urine output, further aiding in blood pressure reduction.
- Dosage Form: Available in tablet form, typically in packs of 30 tablets.
Indications
Telmisartan 80-H is indicated for:
- Hypertension: Used when a single antihypertensive agent is insufficient for controlling blood pressure.
- Cardiovascular Risk Reduction: May be prescribed to lower the risk of cardiovascular events in patients with high blood pressure and additional risk factors.
Mechanism of Action
- Telmisartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict. By preventing this action, telmisartan helps to relax and widen blood vessels.
- Hydrochlorothiazide increases the excretion of sodium and water from the body, which helps to decrease blood volume and subsequently lower blood pressure.
Dosage and Administration
- Recommended Dosage: The usual starting dose is one tablet (80 mg telmisartan and 12.5 mg hydrochlorothiazide) taken once daily. The dosage may be adjusted based on individual patient response and tolerability.
- Administration: Can be taken with or without food. It is important to take it at the same time each day for optimal results.
Side Effects
Common side effects may include:
- Dizziness or light-headedness
- Fatigue
- Nausea or vomiting
- Diarrhea
- Back pain
- Sinus pain or congestion
Serious side effects that require immediate medical attention include:
- Signs of an allergic reaction (e.g., hives, difficulty breathing)
- Swelling of the face, lips, tongue, or throat
- Severe dizziness or fainting
- Unusual changes in urination
Precautions
- Contraindications: Not recommended for individuals with known allergies to telmisartan or hydrochlorothiazide, those with severe kidney problems, or during pregnancy (especially in the second and third trimesters).
- Drug Interactions: Inform your healthcare provider about all medications you are taking to avoid potential interactions.
- Monitoring: Regular monitoring of blood pressure and kidney function may be necessary during treatment.
