Zentel 400mg Tablets are an anthelmintic medication containing albendazole, used primarily for treating various parasitic worm infections. This medication is effective against a range of intestinal and tissue parasites.
Key Features
- Active Ingredient: Each tablet contains 400 mg of albendazole.
- Formulation: Available in a tablet form, typically packaged as 1 tablet per strip.
Indications
Zentel is indicated for the treatment of:
- Intestinal Worm Infections: Effective against:
- Roundworms (Ascaris)
- Hookworms (Ancylostoma, Necator)
- Whipworms (Trichuris)
- Pinworms (Enterobius)
- Tapeworms (Taenia)
- Tissue Infections: Such as:
- Neurocysticercosis (caused by pork tapeworm)
- Cystic hydatid disease (caused by dog tapeworm)
Mechanism of Action
Albendazole works by inhibiting the polymerization of tubulin in parasitic worms, disrupting their metabolism and leading to energy depletion. This results in the immobilization and eventual death of the parasites.
Dosage and Administration
- Recommended Dosage: The typical dosage for adults and children over 2 years is usually 1 tablet (400 mg) taken as a single dose. For specific infections, the dosage may vary based on the physician's recommendation.
- Administration Tips: Swallow the tablet whole with water. It is most effective when taken with a fiber-rich meal.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Dizziness
- Temporary hair loss
Serious side effects requiring immediate medical attention include:
- Signs of an allergic reaction (e.g., rash, swelling, difficulty breathing).
- Fever, chills, sore throat, or other signs of infection.
- Unusual bleeding or bruising.
- Liver function abnormalities indicated by jaundice (yellowing of skin or eyes).
Precautions
- Contraindications: Not recommended for individuals with known hypersensitivity to albendazole or any other components of the medication. Caution is advised for those with liver disease or bone marrow suppression.
- Pregnancy and Breastfeeding: Should not be used during pregnancy unless clearly needed. Consult a healthcare provider before use if pregnant or breastfeeding.
- Drug Interactions: Inform your doctor about any other medications being taken to avoid potential interactions.
